Dupuytren’s Contracture Treatment

Dupuytren’s contracture is a hand deformity caused by the gradual shortening and thickening of the connective tissues (palmar aponeurosis) within the palm.

Dupuytren’s contracture is a genetically inherited disorder. The exact mechanism as to how Dupuytren’s contracture occurs is unknown; however, it is known that there are multiple genes that are involved. This characteristic makes its presentation and behavior different in every individual.

For many people, Dupuytren’s contractures present as thickening of the palmar aponeurosis tissue, are non-progressive, and true contractures do not occur. Observation is recommended for these patients.

In other cases, Dupuytren’s contractures are progressive. In these situations, invasive intervention is recommended. This can be done with injectable medication, collagenase (Xiaflex), or by surgical release/removal of affected tissue.